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Substrate Activation in Flavin-Dependent Thymidylate Synthase
[Image: see text] Thymidylate is a critical DNA nucleotide that has to be synthesized in cells de novo by all organisms. Flavin-dependent thymidylate synthase (FDTS) catalyzes the final step in this de novo production of thymidylate in many human pathogens, but it is absent from humans. The FDTS rea...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121000/ https://www.ncbi.nlm.nih.gov/pubmed/25025487 http://dx.doi.org/10.1021/ja506108b |