Effects of Inactivated Bordetella pertussis on Phosphodiesterase in the Lung of Ovalbumin Sensitized and Challenged Rats

This paper indicated that inactivated Bordetella pertussis (iBp) can enhance the lung airway hyperreactivity of the rats sensitized and challenged with OVA. The mechanisms were involved in the upregulation of cAMP-PDE activity and PDE4A, PDE4D, and PDE3 gene expression in the lungs. But only PDE4 ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Ya-Juan, Song, Shun-De, Chen, Jun-Chun, Wang, Xue-Feng, Jiang, Ya-Li, Xie, Qiang-Min, Chen, Ji-Qiang, Li, Zi-Gang, Tang, Hui-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121004/
https://www.ncbi.nlm.nih.gov/pubmed/25120928
http://dx.doi.org/10.1155/2014/581738

Ejemplares similares

Ejemplares similares