Profiling of Biomarkers for the Exposure of Polycyclic Aromatic Hydrocarbons: Lamin-A/C Isoform 3, Poly[ADP-ribose] Polymerase 1, and Mitochondria Copy Number Are Identified as Universal Biomarkers

This study investigated the profiling of polycyclic aromatic hydrocarbon- (PAH-) induced genotoxicity in cell lines and zebrafish. Each type of cells displayed different proportionality of apoptosis. Mitochondrial DNA (mtDNA) copy number was dramatically elevated after 5-day treatment of fluoranthen...

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Detalles Bibliográficos
Autores principales: Kim, Hwan-Young, Kim, Hye-Ran, Kang, Min-Gu, Trang, Nguyen Thi Dai, Baek, Hee-Jo, Moon, Jae-Dong, Shin, Jong-Hee, Suh, Soon-Pal, Ryang, Dong-Wook, Kook, Hoon, Shin, Myung-Geun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121044/
https://www.ncbi.nlm.nih.gov/pubmed/25114913
http://dx.doi.org/10.1155/2014/605135

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