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A p38 MAPK-Mediated Alteration of COX-2/PGE(2) Regulates Immunomodulatory Properties in Human Mesenchymal Stem Cell Aging

Because human mesenchymal stem cells (hMSC) have profound immunomodulatory effects, many attempts have been made to use hMSCs in preclinical and clinical trials. For hMSCs to be used in therapy, a large population of hMSCs must be generated by in vitro expansion. However, the immunomodulatory change...

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Detalles Bibliográficos
Autores principales:	Yu, Kyung-Rok, Lee, Jin Young, Kim, Hyung-Sik, Hong, In-Sun, Choi, Soon Won, Seo, Yoojin, Kang, Insung, Kim, Jae-Jun, Lee, Byung-Chul, Lee, SeungHee, Kurtz, Andreas, Seo, Kwang-Won, Kang, Kyung-Sun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121064/ https://www.ncbi.nlm.nih.gov/pubmed/25090227 http://dx.doi.org/10.1371/journal.pone.0102426

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