Observer Design for a Core Circadian Rhythm Network

The paper investigates the observer design for a core circadian rhythm network in Drosophila and Neurospora. Based on the constructed highly nonlinear differential equation model and the recently proposed graphical approach, we design a rather simple observer for the circadian rhythm oscillator, whi...

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Detalles Bibliográficos
Autor principal: Zhang, Yuhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121104/
https://www.ncbi.nlm.nih.gov/pubmed/25121122
http://dx.doi.org/10.1155/2014/476912
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author Zhang, Yuhuan
author_facet Zhang, Yuhuan
author_sort Zhang, Yuhuan
collection PubMed
description The paper investigates the observer design for a core circadian rhythm network in Drosophila and Neurospora. Based on the constructed highly nonlinear differential equation model and the recently proposed graphical approach, we design a rather simple observer for the circadian rhythm oscillator, which can well track the state of the original system for various input signals. Numerical simulations show the effectiveness of the designed observer. Potential applications of the related investigations include the real-world control and experimental design of the related biological networks.
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spelling pubmed-41211042014-08-12 Observer Design for a Core Circadian Rhythm Network Zhang, Yuhuan ScientificWorldJournal Research Article The paper investigates the observer design for a core circadian rhythm network in Drosophila and Neurospora. Based on the constructed highly nonlinear differential equation model and the recently proposed graphical approach, we design a rather simple observer for the circadian rhythm oscillator, which can well track the state of the original system for various input signals. Numerical simulations show the effectiveness of the designed observer. Potential applications of the related investigations include the real-world control and experimental design of the related biological networks. Hindawi Publishing Corporation 2014 2014-07-08 /pmc/articles/PMC4121104/ /pubmed/25121122 http://dx.doi.org/10.1155/2014/476912 Text en Copyright © 2014 Yuhuan Zhang. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Zhang, Yuhuan
Observer Design for a Core Circadian Rhythm Network
title Observer Design for a Core Circadian Rhythm Network
title_full Observer Design for a Core Circadian Rhythm Network
title_fullStr Observer Design for a Core Circadian Rhythm Network
title_full_unstemmed Observer Design for a Core Circadian Rhythm Network
title_short Observer Design for a Core Circadian Rhythm Network
title_sort observer design for a core circadian rhythm network
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121104/
https://www.ncbi.nlm.nih.gov/pubmed/25121122
http://dx.doi.org/10.1155/2014/476912
work_keys_str_mv AT zhangyuhuan observerdesignforacorecircadianrhythmnetwork

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