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A Physically-Modified Saline Suppresses Neuronal Apoptosis, Attenuates Tau Phosphorylation and Protects Memory in an Animal Model of Alzheimer's Disease

Alzheimer's disease (AD), the leading cause of dementia in the aging population, is characterized by the presence of neuritic plaques, neurofibrillary tangles and extensive neuronal apoptosis. Neuritic plaques are mainly composed of aggregates of amyloid-β (Aβ) protein while neurofibrillary tan...

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Detalles Bibliográficos
Autores principales:	Modi, Khushbu K., Jana, Arundhati, Ghosh, Supurna, Watson, Richard, Pahan, Kalipada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121132/ https://www.ncbi.nlm.nih.gov/pubmed/25089827 http://dx.doi.org/10.1371/journal.pone.0103606

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