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Effects of Nrf2 Deficiency on Bone Microarchitecture in an Experimental Model of Osteoporosis

Objective. Redox imbalance contributes to bone fragility. We have evaluated the in vivo role of nuclear factor erythroid derived 2-related factor-2 (Nrf2), an important regulator of cellular responses to oxidative stress, in bone metabolism using a model of postmenopausal osteoporosis. Methods. Ovar...

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Detalles Bibliográficos
Autores principales: Ibáñez, Lidia, Ferrándiz, María Luisa, Brines, Rita, Guede, David, Cuadrado, Antonio, Alcaraz, Maria José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121150/
https://www.ncbi.nlm.nih.gov/pubmed/25120886
http://dx.doi.org/10.1155/2014/726590

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