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Regulation of Nasal Airway Homeostasis and Inflammation in Mice by SHP-1 and Th2/Th1 Signaling Pathways

Allergic rhinitis is a chronic inflammatory disease orchestrated by Th2 lymphocytes. Src homology 2 domain-containing protein tyrosine phosphatase (SHP)-1 is known to be a negative regulator in the IL-4α/STAT-6 signaling pathway of the lung. However, the role of SHP-1 enzyme and its functional relat...

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Detalles Bibliográficos
Autores principales:	Cho, Seok Hyun, Oh, Sun Young, Lane, Andrew P., Lee, Joan, Oh, Min-Hee, Lee, Seakwoo, Zheng, Tao, Zhu, Zhou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121172/ https://www.ncbi.nlm.nih.gov/pubmed/25090641 http://dx.doi.org/10.1371/journal.pone.0103685

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