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Andrographolide Inhibits Nuclear Factor-κB Activation through JNK-Akt-p65 Signaling Cascade in Tumor Necrosis Factor-α-Stimulated Vascular Smooth Muscle Cells

Critical vascular inflammation leads to vascular dysfunction and cardiovascular diseases, including abdominal aortic aneurysms, hypertension, and atherosclerosis. Andrographolide is the most active and critical constituent isolated from the leaves of Andrographis paniculata, a herbal medicine widely...

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Detalles Bibliográficos
Autores principales: Chen, Yu-Ying, Hsu, Ming-Jen, Hsieh, Cheng-Ying, Lee, Lin-Wen, Chen, Zhih-Cherng, Sheu, Joen-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121194/
https://www.ncbi.nlm.nih.gov/pubmed/25114952
http://dx.doi.org/10.1155/2014/130381