Cargando…
Osteocyte-Specific Deletion of Fgfr1 Suppresses FGF23
Increases in fibroblastic growth factor 23 (FGF23 or Fgf23) production by osteocytes result in hypophosphatemia and rickets in the Hyp mouse homologue of X-linked hypophosphatemia (XLH). Fibroblastic growth factor (FGF) signaling has been implicated in the pathogenesis of Hyp. Here, we conditionally...
Autores principales: | Xiao, Zhousheng, Huang, Jinsong, Cao, Li, Liang, Yingjuan, Han, Xiaobin, Quarles, Leigh Darryl |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121311/ https://www.ncbi.nlm.nih.gov/pubmed/25089825 http://dx.doi.org/10.1371/journal.pone.0104154 |
Ejemplares similares
-
Osteoblast-Specific Deletion of Pkd2 Leads to Low-Turnover Osteopenia and Reduced Bone Marrow Adiposity
por: Xiao, Zhousheng, et al.
Publicado: (2014) -
Conditional Deletion of Fgfr1 in the Proximal and Distal Tubule Identifies Distinct Roles in Phosphate and Calcium Transport
por: Han, Xiaobin, et al.
Publicado: (2016) -
Role of Fibroblast Growth Factor-23 in Innate Immune Responses
por: Fitzpatrick, Elizabeth A., et al.
Publicado: (2018) -
Osteocytic FGF23 and Its Kidney Function
por: Agoro, Rafiou, et al.
Publicado: (2020) -
A computationally identified compound antagonizes excess FGF-23 signaling in renal tubules and a mouse model of hypophosphatemia
por: Xiao, Zhousheng, et al.
Publicado: (2016)