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Osteocyte-Specific Deletion of Fgfr1 Suppresses FGF23

Increases in fibroblastic growth factor 23 (FGF23 or Fgf23) production by osteocytes result in hypophosphatemia and rickets in the Hyp mouse homologue of X-linked hypophosphatemia (XLH). Fibroblastic growth factor (FGF) signaling has been implicated in the pathogenesis of Hyp. Here, we conditionally...

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Detalles Bibliográficos
Autores principales: Xiao, Zhousheng, Huang, Jinsong, Cao, Li, Liang, Yingjuan, Han, Xiaobin, Quarles, Leigh Darryl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121311/
https://www.ncbi.nlm.nih.gov/pubmed/25089825
http://dx.doi.org/10.1371/journal.pone.0104154

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