Cargando…

Low Levels of the Reverse Transactivator Fail to Induce Target Transgene Expression in Vascular Smooth Muscle Cells

Hutchinson-Gilford progeria syndrome (HGPS) is a genetic disease with multiple features that are suggestive of premature aging. Most patients with HGPS carry a mutation on one of their copies of the LMNA gene. The LMNA gene encodes the lamin A and lamin C proteins, which are the major proteins of th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Viceconte, Nikenza, McKenna, Tomás, Eriksson, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121313/ https://www.ncbi.nlm.nih.gov/pubmed/25090270 http://dx.doi.org/10.1371/journal.pone.0104098

Ejemplares similares

Embryonic expression of the common progeroid lamin A splice mutation arrests postnatal skin development
por: McKenna, Tomás, et al.
Publicado: (2014)

Rare progerin-expressing preadipocytes and adipocytes contribute to tissue depletion over time
por: Revêchon, Gwladys, et al.
Publicado: (2017)

A previously functional tetracycline-regulated transactivator fails to target gene expression to the bone
por: Schmidt, Eva, et al.
Publicado: (2011)

GPCR transactivation signalling in vascular smooth muscle cells: role of NADPH oxidases and reactive oxygen species
por: Mohamed, Raafat, et al.
Publicado: (2019)

Gαq Is the Specific Mediator of PAR-1 Transactivation of Kinase Receptors in Vascular Smooth Muscle Cells
por: Kamato, Danielle, et al.
Publicado: (2022)

Vascular calcification is coupled with phenotypic conversion of vascular smooth muscle cells through Klf5-mediated transactivation of the Runx2 promoter
por: Zhang, Jing, et al.
Publicado: (2014)

Phytanic acid activates NADPH oxidase through transactivation of epidermal growth factor receptor in vascular smooth muscle cells
por: Dhaunsi, Gursev S., et al.
Publicado: (2016)

Lipopolysaccharide acting via toll-like receptor 4 transactivates the TGF-β receptor in vascular smooth muscle cells
por: Afroz, Rizwana, et al.
Publicado: (2022)

RNA sequencing to determine the contribution of kinase receptor transactivation to G protein coupled receptor signalling in vascular smooth muscle cells
por: Kamato, Danielle, et al.
Publicado: (2017)

Matrix metalloproteinase-2-induced epidermal growth factor receptor transactivation impairs redox balance in vascular smooth muscle cells and facilitates vascular contraction
por: Prado, Alejandro F., et al.
Publicado: (2018)

Conditional Reverse Tet-Transactivator Mouse Strains for the Efficient Induction of TRE-Regulated Transgenes in Mice
por: Dow, Lukas E., et al.
Publicado: (2014)

Protein Degradation by Gammaherpesvirus RTAs: More Than Just Viral Transactivators
por: Combs, Lauren R., et al.
Publicado: (2023)

Protease-Activated Receptor 2 Promotes Pro-Atherogenic Effects through Transactivation of the VEGF Receptor 2 in Human Vascular Smooth Muscle Cells
por: Indrakusuma, Ira, et al.
Publicado: (2017)

An α-Smooth Muscle Actin (acta2/αsma) Zebrafish Transgenic Line Marking Vascular Mural Cells and Visceral Smooth Muscle Cells
por: Whitesell, Thomas R., et al.
Publicado: (2014)

Alpha1a-Adrenoceptor Genetic Variant Triggers Vascular Smooth Muscle Cell Hyperproliferation and Agonist Induced Hypertrophy via EGFR Transactivation Pathway
por: Gradinaru, Irina, et al.
Publicado: (2015)

Contribution of oxidative stress and growth factor receptor transactivation in natriuretic peptide receptor C-mediated attenuation of hyperproliferation of vascular smooth muscle cells from SHR
por: Rahali, Sofiane, et al.
Publicado: (2018)

Permanently proliferating rat vascular smooth muscle cell with maintained expression of smooth muscle characteristics, including actin of the vascular smooth muscle type
Publicado: (1980)

Nuclear Smooth Muscle α-actin in Vascular Smooth Muscle Cell Differentiation
por: Kwartler, Callie S., et al.
Publicado: (2023)

THICK FILAMENTS IN VASCULAR SMOOTH MUSCLE
por: Devine, Carrick E., et al.
Publicado: (1971)

Vascular smooth muscle contraction in hypertension
por: Touyz, Rhian M, et al.
Publicado: (2018)

Guidance Molecules in Vascular Smooth Muscle
por: Finney, Alexandra Christine, et al.
Publicado: (2018)

EPAC in Vascular Smooth Muscle Cells
por: Wehbe, Nadine, et al.
Publicado: (2020)

Inhaled tolafentrine reverses pulmonary vascular remodeling via inhibition of smooth muscle cell migration
por: Pullamsetti, Soni, et al.
Publicado: (2005)

AGEs-Induced Calcification and Apoptosis in Human Vascular Smooth Muscle Cells Is Reversed by Inhibition of Autophagy
por: He, Hu-Qiang, et al.
Publicado: (2021)

Qingxuan Jiangya Decoction Reverses Vascular Remodeling by Inducing Vascular Smooth Muscle Cell Apoptosis in Spontaneously Hypertensive Rats
por: Xiao, Fei, et al.
Publicado: (2016)

Aptamer‐Mediated Reversible Transactivation of Gene Expression by Light
por: Renzl, Christian, et al.
Publicado: (2020)

REVERSIBLE DISAGGREGATION OF MYOFILAMENTS IN VERTEBRATE SMOOTH MUSCLE
por: Fay, Fredric S., et al.
Publicado: (1973)

Mechanisms of Vascular Smooth Muscle Contraction and the Basis for Pharmacologic Treatment of Smooth Muscle Disorders
por: Brozovich, F.V., et al.
Publicado: (2016)

Establishment of a conditional transgenic mouse model expressing human uncoupling protein 2 in vascular smooth muscle cells
por: MA, SHUANGTAO, et al.
Publicado: (2012)

Transactivation by low and high levels of human p53 reveals new physical rules of engagement and novel super-transactivation sequences
por: Menendez, Daniel, et al.
Publicado: (2012)

Targeting smooth muscle cell phenotypic switching in vascular disease
por: Chakraborty, Raja, et al.
Publicado: (2021)

Magnesium Inhibits Wnt/β-Catenin Activity and Reverses the Osteogenic Transformation of Vascular Smooth Muscle Cells
por: Montes de Oca, Addy, et al.
Publicado: (2014)

Vascular smooth muscle cell differentiation-2010
por: Miano, Joseph M.
Publicado: (2010)

Origin and differentiation of vascular smooth muscle cells
por: Wang, Gang, et al.
Publicado: (2015)

Senescence in Vascular Smooth Muscle Cells and Atherosclerosis
por: Zha, Yiwen, et al.
Publicado: (2022)

Vascular smooth muscle cell dysfunction in neurodegeneration
por: Hayes, Genevieve, et al.
Publicado: (2022)

Variability of Inducible Expression across the Hematopoietic System of Tetracycline Transactivator Transgenic Mice
por: Takiguchi, Megumi, et al.
Publicado: (2013)

Improvement of the reverse tetracycline transactivator by single amino acid substitutions that reduce leaky target gene expression to undetectable levels
por: Roney, Ian J., et al.
Publicado: (2016)

Regulation of total LC3 levels by angiotensin II in vascular smooth muscle cells
por: Mondaca‐Ruff, David, et al.
Publicado: (2022)

Physiological levels of cardiolipin acutely affect mitochondrial respiration in vascular smooth muscle cells
por: Galambo, Deema, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ek5okdhc7904igoue025thvmgt