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A potential therapeutic effect of CYP2C8 overexpression on anti-TNF-α activity

Epoxyeicosatrienoic acids (EETs) are generated from arachidonic acid catalysed by cytochrome P450 (CYP) epoxygenases. In addition to regulating vascular tone EETs may alleviate inflammation and ROS. The present study was conducted to determine whether CYP2C8 gene overexpression was able to increase...

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Detalles Bibliográficos
Autores principales: LIU, WANJUN, WANG, BEI, DING, HU, WANG, DAO WEN, ZENG, HESONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121355/
https://www.ncbi.nlm.nih.gov/pubmed/25017038
http://dx.doi.org/10.3892/ijmm.2014.1844