Cargando…

A potential therapeutic effect of CYP2C8 overexpression on anti-TNF-α activity

Mostrar otras versiones (1)

Epoxyeicosatrienoic acids (EETs) are generated from arachidonic acid catalysed by cytochrome P450 (CYP) epoxygenases. In addition to regulating vascular tone EETs may alleviate inflammation and ROS. The present study was conducted to determine whether CYP2C8 gene overexpression was able to increase...

Descripción completa

Detalles Bibliográficos
Autores principales:	LIU, WANJUN, WANG, BEI, DING, HU, WANG, DAO WEN, ZENG, HESONG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121355/ https://www.ncbi.nlm.nih.gov/pubmed/25017038 http://dx.doi.org/10.3892/ijmm.2014.1844

Ejemplares similares

A potential therapeutic effect of CYP2C8 overexpression on anti-TNF-α activity
por: Liu, Wanjun, et al.
Publicado: (2023)

CYP2J2 and its metabolites (epoxyeicosatrienoic acids) attenuate cardiac hypertrophy by activating AMPKα2 and enhancing nuclear translocation of Akt1
por: Wang, Bei, et al.
Publicado: (2016)

Overexpressed NEDD8 as a potential therapeutic target in esophageal squamous cell carcinoma
por: Xian, Jingrong, et al.
Publicado: (2022)

Therapeutic Potential of TNF-α Inhibition for Alzheimer’s Disease Prevention
por: Torres-Acosta, Noel, et al.
Publicado: (2020)

Age determines response to anti-TNFα treatment in patients with ankylosing spondylitis and is related to TNFα-producing CD8 cells
por: Schramm-Luc, Agata, et al.
Publicado: (2018)

Assessment of Anti-TNF-α Activities in Keratinocytes Expressing Inducible TNF- α: A Novel Tool for Anti-TNF-α Drug Screening
por: Udommethaporn, Sutthirat, et al.
Publicado: (2016)

TNF-α/anti-TNF-α drugs and its effect on pregnancy outcomes
por: Dai, Fang-fang, et al.
Publicado: (2022)

The Role of TNF-α and Anti-TNF-α Agents during Preconception, Pregnancy, and Breastfeeding
por: Romanowska-Próchnicka, Katarzyna, et al.
Publicado: (2021)

CYP450 Epoxygenase Metabolites, Epoxyeicosatrienoic Acids, as Novel Anti-Inflammatory Mediators
por: Shi, Zeqi, et al.
Publicado: (2022)

Endothelium‐specific CYP2J2 overexpression attenuates age‐related insulin resistance
por: Yang, Yan, et al.
Publicado: (2018)

CD14 overexpression upregulates TNF-α-mediated inflammatory responses and suppresses the malignancy of gastric carcinoma cells
por: Li, Kang, et al.
Publicado: (2013)

Transmembrane TNF-α: structure, function and interaction with anti-TNF agents
por: Horiuchi, Takahiko, et al.
Publicado: (2010)

Therapeutic potential of TNFα inhibitors in chronic inflammatory disorders: Past and future
por: Zhang, Hongtao, et al.
Publicado: (2020)

Intestinal-Specific TNFα Overexpression Induces Crohn’s-Like Ileitis in Mice
por: Bamias, Giorgos, et al.
Publicado: (2013)

Overexpression of TNFα induces senescence, autophagy and mitochondrial dysfunctions in melanoma cells
por: Tyciakova, Silvia, et al.
Publicado: (2021)

Anti-TNF-α Therapy for Ankylosing Spondylitis
por: Son, Jung-Hwan, et al.
Publicado: (2010)

Anti-TNF-α therapy in membranous glomerulonephritis
por: Santoro, Domenico, et al.
Publicado: (2012)

Mollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-α-Induced NF-κB Activation
por: Wang, Zhe, et al.
Publicado: (2017)

TNF-α Induced the Enhanced Apoptosis of Mesenchymal Stem Cells in Ankylosing Spondylitis by Overexpressing TRAIL-R2
por: Liu, Zhenhua, et al.
Publicado: (2017)

Therapeutic Drug Monitoring of Anti-TNFα Inhibitors: A Matter of Cut-Off Ranges
por: Cheli, Stefania, et al.
Publicado: (2023)

TNF-α is a potential therapeutic target to overcome sorafenib resistance in hepatocellular carcinoma
por: Tan, Wenliang, et al.
Publicado: (2018)

The Role of Tumor Necrosis Factor Alpha (TNF-α) in Autoimmune Disease and Current TNF-α Inhibitors in Therapeutics
por: Jang, Dan-in, et al.
Publicado: (2021)

Anti-TNF drives regulatory T cell expansion by paradoxically promoting membrane TNF–TNF-RII binding in rheumatoid arthritis
por: Nguyen, Dao Xuan, et al.
Publicado: (2016)

Harmful Effects and Potential Benefits of Anti-Tumor Necrosis Factor (TNF)-α on the Liver
por: Lopetuso, Loris Riccardo, et al.
Publicado: (2018)

Salivary IL-8, IL-6 and TNF-α as Potential Diagnostic Biomarkers for Oral Cancer
por: Sahibzada, Haafsa Arshad, et al.
Publicado: (2017)

The intensity of joint pain in relation to changes in serum TNFα during therapy with anti-TNFα inhibitors
por: Sikorska, Dorota, et al.
Publicado: (2019)

Differential Expression of Serum Proinflammatory Cytokine TNF-α and Genetic Determinants of TNF-α, CYP2C19*17, miR-423 Genes and Their Effect on Coronary Artery Disease Predisposition and Progression
por: Almassabi, Rehab F., et al.
Publicado: (2023)

Anti-TNF-α Therapies in Systemic Lupus Erythematosus
por: Zhu, Lang-Jing, et al.
Publicado: (2010)

Autoimmune Hepatitis Triggered by Anti-TNF-α Therapy
por: Nakayama, Satoshi
Publicado: (2013)

Anti-TNF-α and hydralazine drug-induced lupus
por: Quaresma, Maria Victória, et al.
Publicado: (2015)

Effects of anti-TNF-α in experimental diversion colitis
por: Buanaim, Ronaldo Parisi, et al.
Publicado: (2019)

Anti-TNF-α Compounds as a Treatment for Depression
por: Uzzan, Sarit, et al.
Publicado: (2021)

Establishment of a meta-analysis based novel aortic dissection mouse model
por: Jiang, Hongcheng, et al.
Publicado: (2022)

Anti-TNF-α Drugs Differently Affect the TNFα-sTNFR System and Monocyte Subsets in Patients with Psoriasis
por: Gibellini, Lara, et al.
Publicado: (2016)

Overexpression of TNF causes bilateral sacroiliitis
por: Redlich, K, et al.
Publicado: (2004)

CYP2C8 *3 and *4 define CYP2C8 phenotype: An approach with the substrate cinitapride
por: Campodónico, Diana María, et al.
Publicado: (2022)

Systemic Overexpression of TNFα-converting Enzyme Does Not Lead to Enhanced Shedding Activity In Vivo
por: Yoda, Masaki, et al.
Publicado: (2013)

TRPM8 in the negative regulation of TNFα expression during cold stress
por: Wang, Xin-Pei, et al.
Publicado: (2017)

Aortic Coarctation Associated With Hypertrophic Cardiomyopathy in a Woman With Hypertension and Syncope: A Case Report With 8-Year Follow-Up
por: Yang, Hong, et al.
Publicado: (2022)

Obstructive sleep apnea syndrome promotes the progression of aortic dissection via a ROS- HIF-1α-MMPs associated pathway
por: Liu, Wanjun, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_n2k8tiftudcqcafro5cohu77e0