Cargando…
Widespread differences in cortex DNA methylation of the “language gene” CNTNAP2 between humans and chimpanzees
CNTNAP2, one of the largest genes in the human genome, has been linked to human-specific language abilities and neurodevelopmental disorders. Our hypothesis is that epigenetic rather than genetic changes have accelerated the evolution of the human brain. To compare the cortex DNA methylation pattern...
Autores principales: | Schneider, Eberhard, El Hajj, Nady, Richter, Steven, Roche-Santiago, Justin, Nanda, Indrajit, Schempp, Werner, Riederer, Peter, Navarro, Bianca, Bontrop, Ronald E, Kondova, Ivanela, Scholz, Claus Jürgen, Haaf, Thomas |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121364/ https://www.ncbi.nlm.nih.gov/pubmed/24434791 http://dx.doi.org/10.4161/epi.27689 |
Ejemplares similares
-
Cell Type and Species-specific Patterns in Neuronal and Non-neuronal Methylomes of Human and Chimpanzee Cortices
por: Böck, Julia, et al.
Publicado: (2018) -
Origins of De Novo Genes in Human and Chimpanzee
por: Ruiz-Orera, Jorge, et al.
Publicado: (2015) -
Epigenetic dysregulation in the developing Down syndrome cortex
por: El Hajj, Nady, et al.
Publicado: (2016) -
Insights on the functional interactions between miRNAs and copy number variations in the aging brain
por: Persengiev, Stephan, et al.
Publicado: (2013) -
Complete Genome Sequence of a Novel Chimpanzee Polyomavirus from a Western Common Chimpanzee
por: van Persie, Jolanda, et al.
Publicado: (2016)