BET bromodomain proteins are required for glioblastoma cell proliferation

Epigenetic proteins have recently emerged as novel anticancer targets. Among these, bromodomain and extra terminal domain (BET) proteins recognize lysine-acetylated histones, thereby regulating gene expression. Newly described small molecules that inhibit BET proteins BRD2, BRD3, and BRD4 reduce pro...

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Detalles Bibliográficos
Autores principales: Pastori, Chiara, Daniel, Mark, Penas, Clara, Volmar, Claude-Henry, Johnstone, Andrea L, Brothers, Shaun P, Graham, Regina M, Allen, Bryce, Sarkaria, Jann N, Komotar, Ricardo J, Wahlestedt, Claes, Ayad, Nagi G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121371/
https://www.ncbi.nlm.nih.gov/pubmed/24496381
http://dx.doi.org/10.4161/epi.27906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121371/
https://www.ncbi.nlm.nih.gov/pubmed/24496381
http://dx.doi.org/10.4161/epi.27906

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