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NVP-BEZ235, a dual PI3K/mTOR inhibitor synergistically potentiates the antitumor effects of cisplatin in bladder cancer cells

The PI3K/Akt/mTOR pathway is a prototypic survival pathway and constitutively activated in many malignant conditions. Moreover, activation of the PI3K/Akt/mTOR pathway confers resistance to various cancer therapies and is often associated with a poor prognosis. In this study, we explored the antitum...

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Detalles Bibliográficos
Autores principales:	MOON, DU G., LEE, SANG E., OH, MI M., LEE, SANG C., JEONG, SEONG J., HONG, SUNG K., YOON, CHEOL Y., BYUN, SEOK S., PARK, HONG S., CHEON, JUN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2014
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121414/ https://www.ncbi.nlm.nih.gov/pubmed/24969552 http://dx.doi.org/10.3892/ijo.2014.2505

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