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Vitamin C enhances anticancer activity in methotrexate-treated Hep3B hepatocellular carcinoma cells
Methotrexate (MTX) has been widely used for rheumatoid arthritis therapy for a long time. MTX is also used as an anticancer drug for various tumors. However, many studies have shown that high-dose MTX treatment for cancer therapy may cause liver and renal damage. Alhough the mechanisms involved in M...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121419/ https://www.ncbi.nlm.nih.gov/pubmed/24969544 http://dx.doi.org/10.3892/or.2014.3289 |