Attenuated ability of BACE1 to cleave the amyloid precursor protein via silencing long noncoding RNA BACE1-AS expression

Although large numbers of long noncoding RNAs (lncRNAs) expressed in the mammalian nervous system have been detected, their functions and mechanisms of regulation remain to be fully clarified. It has been reported that the lncRNA antisense transcript for β-secretase-1 (BACE1-AS) is elevated in Alzhe...

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Autores principales: LIU, TE, HUANG, YONGYI, CHEN, JIULIN, CHI, HUIYING, YU, ZHIHUA, WANG, JIAN, CHEN, CHUAN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121421/
https://www.ncbi.nlm.nih.gov/pubmed/24970022
http://dx.doi.org/10.3892/mmr.2014.2351

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