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Elevated expression levels of miR-143/5 in saphenous vein smooth muscle cells from patients with Type 2 diabetes drive persistent changes in phenotype and function
Type 2 diabetes (T2DM) promotes premature atherosclerosis and inferior prognosis after arterial reconstruction. Vascular smooth muscle cells (SMC) respond to patho/physiological stimuli, switching between quiescent contractile and activated synthetic phenotypes under the control of microRNAs (miRs)...
Autores principales: | Riches, Kirsten, Alshanwani, Aliah R., Warburton, Philip, O’Regan, David J., Ball, Stephen G., Wood, Ian C., Turner, Neil A., Porter, Karen E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121534/ https://www.ncbi.nlm.nih.gov/pubmed/24927876 http://dx.doi.org/10.1016/j.yjmcc.2014.05.018 |
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