Cargando…
Interleukin-1β mediates macrophage-induced impairment of insulin signaling in human primary adipocytes
Adipose tissue expansion during obesity is associated with increased macrophage infiltration. Macrophage-derived factors significantly alter adipocyte function, inducing inflammatory responses and decreasing insulin sensitivity. Identification of the major factors that mediate detrimental effects of...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121578/ https://www.ncbi.nlm.nih.gov/pubmed/24918199 http://dx.doi.org/10.1152/ajpendo.00430.2013 |