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Interleukin-1β mediates macrophage-induced impairment of insulin signaling in human primary adipocytes
Adipose tissue expansion during obesity is associated with increased macrophage infiltration. Macrophage-derived factors significantly alter adipocyte function, inducing inflammatory responses and decreasing insulin sensitivity. Identification of the major factors that mediate detrimental effects of...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Physiological Society
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121578/ https://www.ncbi.nlm.nih.gov/pubmed/24918199 http://dx.doi.org/10.1152/ajpendo.00430.2013 |