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Extracellular iron diminishes anticancer effects of vitamin C: An in vitro study

In vitro studies have shown that hydrogen peroxide (H(2)O(2)) produced by high-concentration ascorbate and cell culture medium iron efficiently kills cancer cells. This provided the rationale for clinical trials of high-dose intravenous ascorbate-based treatment for cancer. A drawback in all the in...

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Detalles Bibliográficos
Autores principales:	Mojić, Marija, Pristov, Jelena Bogdanović, Maksimović-Ivanić, Danijela, Jones, David R., Stanić, Marina, Mijatović, Sanja, Spasojević, Ivan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121606/ https://www.ncbi.nlm.nih.gov/pubmed/25092529 http://dx.doi.org/10.1038/srep05955

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