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NAD-dependent isocitrate dehydrogenase as a novel target of tributyltin in human embryonic carcinoma cells

Tributyltin (TBT) is known to cause developmental defects as endocrine disruptive chemicals (EDCs). At nanomoler concentrations, TBT actions were mediated by genomic pathways via PPAR/RXR. However, non-genomic target of TBT has not been elucidated. To investigate non-genomic TBT targets, we performe...

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Detalles Bibliográficos
Autores principales:	Yamada, Shigeru, Kotake, Yaichiro, Demizu, Yosuke, Kurihara, Masaaki, Sekino, Yuko, Kanda, Yasunari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121607/ https://www.ncbi.nlm.nih.gov/pubmed/25092173 http://dx.doi.org/10.1038/srep05952

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