IFITMs Restrict the Replication of Multiple Pathogenic Viruses

The interferon-inducible transmembrane protein (IFITM) family inhibits a growing number of pathogenic viruses, among them influenza A virus, dengue virus, hepatitis C virus, and Ebola virus. This review covers recent developments in our understanding of the IFITM's molecular determinants, poten...

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Detalles Bibliográficos
Autores principales: Perreira, Jill M., Chin, Christopher R., Feeley, Eric M., Brass, Abraham L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121887/
https://www.ncbi.nlm.nih.gov/pubmed/24076421
http://dx.doi.org/10.1016/j.jmb.2013.09.024
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author Perreira, Jill M.
Chin, Christopher R.
Feeley, Eric M.
Brass, Abraham L.
author_facet Perreira, Jill M.
Chin, Christopher R.
Feeley, Eric M.
Brass, Abraham L.
author_sort Perreira, Jill M.
collection PubMed
description The interferon-inducible transmembrane protein (IFITM) family inhibits a growing number of pathogenic viruses, among them influenza A virus, dengue virus, hepatitis C virus, and Ebola virus. This review covers recent developments in our understanding of the IFITM's molecular determinants, potential mechanisms of action, and impact on pathogenesis.
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spelling pubmed-41218872014-08-05 IFITMs Restrict the Replication of Multiple Pathogenic Viruses Perreira, Jill M. Chin, Christopher R. Feeley, Eric M. Brass, Abraham L. J Mol Biol Article The interferon-inducible transmembrane protein (IFITM) family inhibits a growing number of pathogenic viruses, among them influenza A virus, dengue virus, hepatitis C virus, and Ebola virus. This review covers recent developments in our understanding of the IFITM's molecular determinants, potential mechanisms of action, and impact on pathogenesis. Elsevier Ltd. 2013-12-13 2013-09-25 /pmc/articles/PMC4121887/ /pubmed/24076421 http://dx.doi.org/10.1016/j.jmb.2013.09.024 Text en Copyright © 2013 Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Perreira, Jill M.
Chin, Christopher R.
Feeley, Eric M.
Brass, Abraham L.
IFITMs Restrict the Replication of Multiple Pathogenic Viruses
title IFITMs Restrict the Replication of Multiple Pathogenic Viruses
title_full IFITMs Restrict the Replication of Multiple Pathogenic Viruses
title_fullStr IFITMs Restrict the Replication of Multiple Pathogenic Viruses
title_full_unstemmed IFITMs Restrict the Replication of Multiple Pathogenic Viruses
title_short IFITMs Restrict the Replication of Multiple Pathogenic Viruses
title_sort ifitms restrict the replication of multiple pathogenic viruses
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121887/
https://www.ncbi.nlm.nih.gov/pubmed/24076421
http://dx.doi.org/10.1016/j.jmb.2013.09.024
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