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PDK1-mediated activation of MRCKα regulates directional cell migration and lamellipodia retraction

Directional cell migration is of paramount importance in both physiological and pathological processes, such as development, wound healing, immune response, and cancer invasion. Here, we report that 3-phosphoinositide-dependent kinase 1 (PDK1) regulates epithelial directional migration and invasion...

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Detalles Bibliográficos
Autores principales:	Gagliardi, Paolo Armando, di Blasio, Laura, Puliafito, Alberto, Seano, Giorgio, Sessa, Roberto, Chianale, Federica, Leung, Thomas, Bussolino, Federico, Primo, Luca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2014
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4121984/ https://www.ncbi.nlm.nih.gov/pubmed/25092657 http://dx.doi.org/10.1083/jcb.201312090

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