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Characterisation of an aerosol exposure system to evaluate the genotoxicity of whole mainstream cigarette smoke using the in vitro γH2AX assay by high content screening

BACKGROUND: The genotoxic effect of cigarette smoke is routinely measured by treating cells with cigarette Particulate Matter (PM) at different dose levels in submerged cell cultures. However, PM exposure cannot be considered as a complete exposure as it does not contain the gas phase component of t...

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Detalles Bibliográficos
Autores principales:	Garcia-Canton, Carolina, Errington, Graham, Anadon, Arturo, Meredith, Clive
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122049/ https://www.ncbi.nlm.nih.gov/pubmed/25056295 http://dx.doi.org/10.1186/2050-6511-15-41

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