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Age-Dependent Modifications of AMPA Receptor Subunit Expression Levels and Related Cognitive Effects in 3xTg-AD Mice

GluA1, GluA2, GluA3, and GluA4 are the constitutive subunits of amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs), the major mediators of fast excitatory transmission in the mammalian central nervous system. Most AMPARs are Ca(2+)-impermeable because of the presence of the GluA2...

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Detalles Bibliográficos
Autores principales: Cantanelli, Pamela, Sperduti, Samantha, Ciavardelli, Domenico, Stuppia, Liborio, Gatta, Valentina, Sensi, Stefano Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122177/
https://www.ncbi.nlm.nih.gov/pubmed/25140151
http://dx.doi.org/10.3389/fnagi.2014.00200