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Potency and Stability of Intradermal Capsaicin: Implications for Use as a Human Model of Pain in Multicenter Clinical Trials
Intradermally injected capsaicin has been used extensively both as a human pain model and to assess analgesic efficacy. Factors such as dose, formulation, route, and site are known to affect its sensitivity. We determined whether potency and stability of capsaicin solutions were further sources of v...
Autores principales: | Balabathula, Pavan, Bhattacharjee, Himanshu, Thoma, Laura A, Nolly, Robert J, Horton, Frank P, Stornes, Gwendolyn D, Wan, Jim Y, Brooks, Ian M, Bachmann, Gloria A, Foster, David C, Brown, Candace S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122245/ https://www.ncbi.nlm.nih.gov/pubmed/25105064 http://dx.doi.org/10.4172/2161-1459.1000142 |
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