The Interplay between Natural Selection and Susceptibility to Melanoma on Allele 374F of SLC45A2 Gene in a South European Population

We aimed to study the selective pressures interacting on SLC45A2 to investigate the interplay between selection and susceptibility to disease. Thus, we enrolled 500 volunteers from a geographically limited population (Basques from the North of Spain) and by resequencing the whole coding region and i...

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Detalles Bibliográficos
Autores principales: López, Saioa, García, Óscar, Yurrebaso, Iñaki, Flores, Carlos, Acosta-Herrera, Marialbert, Chen, Hua, Gardeazabal, Jesús, Careaga, Jesús María, Boyano, María Dolores, Sánchez, Ana, Ratón-Nieto, Juan Antonio, Sevilla, Arrate, Smith-Zubiaga, Isabel, de Galdeano, Alicia García, Martinez-Cadenas, Conrado, Izagirre, Neskuts, de la Rúa, Concepción, Alonso, Santos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122405/
https://www.ncbi.nlm.nih.gov/pubmed/25093503
http://dx.doi.org/10.1371/journal.pone.0104367

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