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Diverse Functionalization of Aurora-A Kinase at Specified Surface and Buried Sites by Native Chemical Modification
The ability to obtain a homogeneous sample of protein is invaluable when studying the effect of alterations such as post-translational modifications (PTMs). Selective functionalization of a protein to investigate the effect of PTMs on its structure or activity can be achieved by chemical modificatio...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122486/ https://www.ncbi.nlm.nih.gov/pubmed/25093837 http://dx.doi.org/10.1371/journal.pone.0103935 |