Cargando…
Diverse Functionalization of Aurora-A Kinase at Specified Surface and Buried Sites by Native Chemical Modification
The ability to obtain a homogeneous sample of protein is invaluable when studying the effect of alterations such as post-translational modifications (PTMs). Selective functionalization of a protein to investigate the effect of PTMs on its structure or activity can be achieved by chemical modificatio...
Autores principales: | Rowan, Fiona, Richards, Meirion, Widya, Marcella, Bayliss, Richard, Blagg, Julian |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122486/ https://www.ncbi.nlm.nih.gov/pubmed/25093837 http://dx.doi.org/10.1371/journal.pone.0103935 |
Ejemplares similares
-
Insights into Aurora-A Kinase Activation Using
Unnatural Amino Acids Incorporated by Chemical Modification
por: Rowan, Fiona C., et al.
Publicado: (2013) -
Dynamic Equilibrium of the Aurora A Kinase Activation Loop Revealed by Single‐Molecule Spectroscopy
por: Gilburt, James A. H., et al.
Publicado: (2017) -
Aurora Isoform Selectivity:
Design and Synthesis of
Imidazo[4,5-b]pyridine Derivatives as Highly
Selective Inhibitors of Aurora-A Kinase in Cells
por: Bavetsias, Vassilios, et al.
Publicado: (2013) -
Ligand discrimination between active and inactive activation loop conformations of Aurora-A kinase is unmodified by phosphorylation
por: Gilburt, James A. H., et al.
Publicado: (2019) -
Aurora Kinase A Regulation by Cysteine Oxidative Modification
por: Lee, In-Gyun, et al.
Publicado: (2023)