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Supraspinal gene transfer by intrathecal adeno-associated virus serotype 5
We report the pattern of transgene expression across brain regions after intrathecal delivery of adeno-associated virus serotype 5 (AAV5). Labeling in hindbrain appeared to be primarily neuronal, and was detected in sensory nuclei of medulla, pontine nuclei, and all layers of cerebellar cortex. Expr...
Autores principales: | Schuster, Daniel J., Belur, Lalitha R., Riedl, Maureen S., Schnell, Stephen A., Podetz-Pedersen, Kelly M., Kitto, Kelley F., McIvor, R. Scott, Vulchanova, Lucy, Fairbanks, Carolyn A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122912/ https://www.ncbi.nlm.nih.gov/pubmed/25147505 http://dx.doi.org/10.3389/fnana.2014.00066 |
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