Evolutionary Origin and Methylation Status of Human Intronic CpG Islands that Are Not Present in Mouse

Imprinting of the human RB1 gene is due to the presence of a differentially methylated CpG island (CGI) in intron 2, which is part of a retrocopy derived from the PPP1R26 gene on chromosome 9. The murine Rb1 gene does not have this retrocopy and is not imprinted. We have investigated whether the RB1...

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Detalles Bibliográficos
Autores principales: Rademacher, Katrin, Schröder, Christopher, Kanber, Deniz, Klein-Hitpass, Ludger, Wallner, Stefan, Zeschnigk, Michael, Horsthemke, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122923/
https://www.ncbi.nlm.nih.gov/pubmed/24923327
http://dx.doi.org/10.1093/gbe/evu125

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122923/
https://www.ncbi.nlm.nih.gov/pubmed/24923327
http://dx.doi.org/10.1093/gbe/evu125

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