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Novel VCP modulators mitigate major pathologies of rd10, a mouse model of retinitis pigmentosa
Neuroprotection may prevent or forestall the progression of incurable eye diseases, such as retinitis pigmentosa, one of the major causes of adult blindness. Decreased cellular ATP levels may contribute to the pathology of this eye disease and other neurodegenerative diseases. Here we describe small...
Autores principales: | Ikeda, Hanako Ohashi, Sasaoka, Norio, Koike, Masaaki, Nakano, Noriko, Muraoka, Yuki, Toda, Yoshinobu, Fuchigami, Tomohiro, Shudo, Toshiyuki, Iwata, Ayana, Hori, Seiji, Yoshimura, Nagahisa, Kakizuka, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4122966/ https://www.ncbi.nlm.nih.gov/pubmed/25096051 http://dx.doi.org/10.1038/srep05970 |
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