CXCR4 and CXCR7 transduce through mTOR in human renal cancer cells

Treatment of metastatic renal cell carcinoma (mRCC) has improved significantly with the advent of agents targeting the mTOR pathway, such as temsirolimus and everolimus. However, their efficacy is thought to be limited by feedback loops and crosstalk with other pathways leading to the development of...

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Detalles Bibliográficos
Autores principales: Ieranò, C, Santagata, S, Napolitano, M, Guardia, F, Grimaldi, A, Antignani, E, Botti, G, Consales, C, Riccio, A, Nanayakkara, M, Barone, M V, Caraglia, M, Scala, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123065/
https://www.ncbi.nlm.nih.gov/pubmed/24991762
http://dx.doi.org/10.1038/cddis.2014.269

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