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Inhibition of apoptotic Bax translocation to the mitochondria is a central function of parkin

Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder, affecting 1–3% of the population over 65. Mutations in the ubiquitin E3 ligase parkin are the most common cause of autosomal recessive PD. The parkin protein possesses potent cell-protective properties and has bee...

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Detalles Bibliográficos
Autores principales:	Charan, R A, Johnson, B N, Zaganelli, S, Nardozzi, J D, LaVoie, M J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123072/ https://www.ncbi.nlm.nih.gov/pubmed/24991765 http://dx.doi.org/10.1038/cddis.2014.278

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