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6-Phosphofructo-2-kinase (PFKFB3) promotes cell cycle progression and suppresses apoptosis via Cdk1-mediated phosphorylation of p27

The control of glucose metabolism and the cell cycle must be coordinated in order to guarantee sufficient ATP and anabolic substrates at distinct phases of the cell cycle. The family of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFKFB1-4) are well established regulators of glucose metabo...

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Detalles Bibliográficos
Autores principales:	Yalcin, A, Clem, B F, Imbert-Fernandez, Y, Ozcan, S C, Peker, S, O'Neal, J, Klarer, A C, Clem, A L, Telang, S, Chesney, J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123086/ https://www.ncbi.nlm.nih.gov/pubmed/25032860 http://dx.doi.org/10.1038/cddis.2014.292

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