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JNK1/2 regulate Bid by direct phosphorylation at Thr59 in response to ALDH1L1

BH3 interacting-domain death agonist (Bid) is a BH3-only pro-apoptotic member of the Bcl-2 family of proteins. Its function in apoptosis is associated with the proteolytic cleavage to the truncated form tBid, mainly by caspase-8. tBid translocates to mitochondria and assists Bax and Bak in induction...

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Detalles Bibliográficos
Autores principales:	Prakasam, A, Ghose, S, Oleinik, N V, Bethard, J R, Peterson, Y K, Krupenko, N I, Krupenko, S A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123105/ https://www.ncbi.nlm.nih.gov/pubmed/25077544 http://dx.doi.org/10.1038/cddis.2014.316

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