MAPK signaling mediates sinomenine hydrochloride-induced human breast cancer cell death via both reactive oxygen species-dependent and -independent pathways: an in vitro and in vivo study

Sinomenine, the main alkaloid extracted from the medicinal plant Sinomenium acutum, is known for its anti-inflammatory effects. Recent studies have suggested its anti-cancer effect in synovial sarcoma, lung cancer and hepatic cancer. However, the underlying molecular mechanism for its anti-cancer ef...

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Detalles Bibliográficos
Autores principales: Li, X, Wang, K, Ren, Y, Zhang, L, Tang, X-J, Zhang, H-M, Zhao, C-Q, Liu, P-J, Zhang, J-M, He, J-J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123109/
https://www.ncbi.nlm.nih.gov/pubmed/25077542
http://dx.doi.org/10.1038/cddis.2014.321

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