Dapper1 promotes autophagy by enhancing the Beclin1-Vps34-Atg14L complex formation

Autophagy is an intracellular degradation process to clear up aggregated proteins or aged and damaged organelles. The Beclin1-Vps34-Atg14L complex is essential for autophagosome formation. However, how the complex formation is regulated is unclear. Here, we show that Dapper1 (Dpr1) acts as a critica...

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Detalles Bibliográficos
Autores principales: Ma, Benyu, Cao, Weipeng, Li, Wenxia, Gao, Chan, Qi, Zhen, Zhao, Yan, Du, Jun, Xue, Hua, Peng, Junya, Wen, Jun, Chen, Hua, Ning, Yuanheng, Huang, Lei, Zhang, Hong, Gao, Xiang, Yu, Li, Chen, Ye-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123296/
https://www.ncbi.nlm.nih.gov/pubmed/24980960
http://dx.doi.org/10.1038/cr.2014.84

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