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A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression
Thyroid transcription factor-1 (TTF-1, also known as NKX2-1) is a tissue-specific transcription factor in lung epithelial cells. Although TTF-1 inhibits the epithelial-to-mesenchymal transition induced by transforming growth factor-β (TGF-β) in lung adenocarcinoma cells, the mechanism through which...
Autores principales: | Isogaya, Kazunobu, Koinuma, Daizo, Tsutsumi, Shuichi, Saito, Roy-Akira, Miyazawa, Keiji, Aburatani, Hiroyuki, Miyazono, Kohei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123303/ https://www.ncbi.nlm.nih.gov/pubmed/25060702 http://dx.doi.org/10.1038/cr.2014.97 |
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