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Digital Vasculitis in a Patient with Rheumatoid Arthritis Responded Well to Adalimumab

42-year-old old female patient, followed up with diagnosis of rheumatoid arthritis for 15 years, was admitted with necrotising ulcer of left hand 1st and 2nd fingertips and pain, swelling, limitation of movement, and morning stiffness at bilateral wrist, and metacarpophalangeal and proximal interpha...

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Detalles Bibliográficos
Autores principales: Kobak, Senol, Yilmaz, Hatice, Yalcin, Murat, Karaarslan, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123564/
https://www.ncbi.nlm.nih.gov/pubmed/25133007
http://dx.doi.org/10.1155/2014/416825
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author Kobak, Senol
Yilmaz, Hatice
Yalcin, Murat
Karaarslan, Ahmet
author_facet Kobak, Senol
Yilmaz, Hatice
Yalcin, Murat
Karaarslan, Ahmet
author_sort Kobak, Senol
collection PubMed
description 42-year-old old female patient, followed up with diagnosis of rheumatoid arthritis for 15 years, was admitted with necrotising ulcer of left hand 1st and 2nd fingertips and pain, swelling, limitation of movement, and morning stiffness at bilateral wrist, and metacarpophalangeal and proximal interphalangeal joints. Laboratory tests revealed elevated acute phase reactants. Radial and ulnar arteries were clear in upper extremity Doppler ultrasound. The patient was diagnosed as RA activation and digital ulcer and administered iloprost infusion for five days and 1 mg/kg corticosteroid and 20 mg/week methotrexate (MTX). After one month, a partial regression of clinical and laboratory findings was observed. However, 6 months later, due to relapsed and increased complaints and findings, adalimumab 40 mg was administered. Two months later, clinical and laboratory findings apparently decreased.
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spelling pubmed-41235642014-08-17 Digital Vasculitis in a Patient with Rheumatoid Arthritis Responded Well to Adalimumab Kobak, Senol Yilmaz, Hatice Yalcin, Murat Karaarslan, Ahmet Case Rep Rheumatol Case Report 42-year-old old female patient, followed up with diagnosis of rheumatoid arthritis for 15 years, was admitted with necrotising ulcer of left hand 1st and 2nd fingertips and pain, swelling, limitation of movement, and morning stiffness at bilateral wrist, and metacarpophalangeal and proximal interphalangeal joints. Laboratory tests revealed elevated acute phase reactants. Radial and ulnar arteries were clear in upper extremity Doppler ultrasound. The patient was diagnosed as RA activation and digital ulcer and administered iloprost infusion for five days and 1 mg/kg corticosteroid and 20 mg/week methotrexate (MTX). After one month, a partial regression of clinical and laboratory findings was observed. However, 6 months later, due to relapsed and increased complaints and findings, adalimumab 40 mg was administered. Two months later, clinical and laboratory findings apparently decreased. Hindawi Publishing Corporation 2014 2014-07-15 /pmc/articles/PMC4123564/ /pubmed/25133007 http://dx.doi.org/10.1155/2014/416825 Text en Copyright © 2014 Senol Kobak et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Kobak, Senol
Yilmaz, Hatice
Yalcin, Murat
Karaarslan, Ahmet
Digital Vasculitis in a Patient with Rheumatoid Arthritis Responded Well to Adalimumab
title Digital Vasculitis in a Patient with Rheumatoid Arthritis Responded Well to Adalimumab
title_full Digital Vasculitis in a Patient with Rheumatoid Arthritis Responded Well to Adalimumab
title_fullStr Digital Vasculitis in a Patient with Rheumatoid Arthritis Responded Well to Adalimumab
title_full_unstemmed Digital Vasculitis in a Patient with Rheumatoid Arthritis Responded Well to Adalimumab
title_short Digital Vasculitis in a Patient with Rheumatoid Arthritis Responded Well to Adalimumab
title_sort digital vasculitis in a patient with rheumatoid arthritis responded well to adalimumab
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123564/
https://www.ncbi.nlm.nih.gov/pubmed/25133007
http://dx.doi.org/10.1155/2014/416825
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