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Preclinical Characterization of Recombinant Human Tissue Kallikrein-1 as a Novel Treatment for Type 2 Diabetes Mellitus
Modulation of the kallikrein-kinin system (KKS) has been shown to have beneficial effects on glucose homeostasis and several other physiological responses relevant to the progression of type 2 diabetes mellitus (T2D). The importance of bradykinin and its receptors in mediating these responses is wel...
Autores principales: | Kolodka, Tadeusz, Charles, Matthew L., Raghavan, Arvind, Radichev, Ilian A., Amatya, Christina, Ellefson, Jacob, Savinov, Alexei Y., Nag, Abhijeet, Williams, Mark S., Robbins, Mark S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4123992/ https://www.ncbi.nlm.nih.gov/pubmed/25100328 http://dx.doi.org/10.1371/journal.pone.0103981 |
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