Cargando…
Restoring ciliary function to differentiated Primary Ciliary Dyskinesia cells with a lentiviral vector
Primary ciliary dyskinesia is a genetically heterogeneous autosomal recessive disease in which mutations disrupt ciliary function, leading to impaired mucociliary clearance and life-long lung disease. Mouse tracheal cells with a targeted deletion in the axonemal dynein intermediated chain gene Dnaic...
| Autores principales: | , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124007/ https://www.ncbi.nlm.nih.gov/pubmed/24451115 http://dx.doi.org/10.1038/gt.2013.79 |