Cargando…
PMC, a potent hydrophilic α-tocopherol derivative, inhibits NF-κB activation via PP2A but not IκBα-dependent signals in vascular smooth muscle cells
The hydrophilic α-tocopherol derivative, 2,2,5,7,8-pentamethyl-6-hydroxychromane (PMC), is a promising alternative to vitamin E in clinical applications. Critical vascular inflammation leads to vascular dysfunction and vascular diseases, including atherosclerosis, hypertension and abdominal aortic a...
Autores principales: | Hsieh, Cheng-Ying, Hsiao, George, Hsu, Ming-Jen, Wang, Yi-Hsuan, Sheu, Joen-Rong |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124013/ https://www.ncbi.nlm.nih.gov/pubmed/24725826 http://dx.doi.org/10.1111/jcmm.12277 |
Ejemplares similares
-
Mechanisms of glabridin inhibition of integrin α(IIb)β(3) inside-out signals and NF-κB activation in human platelets
por: Huang, Wei-Chieh, et al.
Publicado: (2023) -
Role of cantharidin in the activation of IKKα/IκBα/NF-κB pathway by inhibiting PP2A activity in cholangiocarcinoma cell lines
por: Zhou, Huijiang, et al.
Publicado: (2018) -
Andrographolide Inhibits Nuclear Factor-κB Activation through JNK-Akt-p65 Signaling Cascade in Tumor Necrosis Factor-α-Stimulated Vascular Smooth Muscle Cells
por: Chen, Yu-Ying, et al.
Publicado: (2014) -
Andrographolide, a Novel NF-κB Inhibitor, Induces Vascular Smooth Muscle Cell Apoptosis via a Ceramide-p47phox-ROS Signaling Cascade
por: Chen, Yu-Ying, et al.
Publicado: (2013) -
Role of Monoubiquitylation on the Control of IκBα Degradation and NF-κB Activity
por: Da Silva-Ferrada, Elisa, et al.
Publicado: (2011)