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TGF-beta signalling in the adult neurogenic niche promotes stem cell quiescence as well as generation of new neurons

Members of the transforming growth factor (TGF)-β family govern a wide range of mechanisms in brain development and in the adult, in particular neuronal/glial differentiation and survival, but also cell cycle regulation and neural stem cell maintenance. This clearly created some discrepancies in the...

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Detalles Bibliográficos
Autores principales: Kandasamy, Mahesh, Lehner, Bernadette, Kraus, Sabrina, Sander, Paul Ramm, Marschallinger, Julia, Rivera, Francisco J, Trümbach, Dietrich, Ueberham, Uwe, Reitsamer, Herbert A, Strauss, Olaf, Bogdahn, Ulrich, Couillard-Despres, Sebastien, Aigner, Ludwig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124027/
https://www.ncbi.nlm.nih.gov/pubmed/24779367
http://dx.doi.org/10.1111/jcmm.12298