RPRD1A and RPRD1B Are Human RNA Polymerase II C-Terminal Domain Scaffolds for Ser5 Dephosphorylation

The RNA polymerase II (RNAPII) carboxyl-terminal domain (CTD) heptapeptide repeats (Y1-S2-P3-T4-S5-P6-S7) undergo dynamic phosphorylation and dephosphorylation during the transcription cycle to recruit factors that regulate transcription, RNA processing and chromatin modification. We show here that...

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Detalles Bibliográficos
Autores principales: Ni, Zuyao, Xu, Chao, Guo, Xinghua, Hunter, Gerald O., Kuznetsova, Olga V., Tempel, Wolfram, Marcon, Edyta, Zhong, Guoqing, Guo, Hongbo, Kuo, Wei-Hung William, Li, Joyce, Young, Peter, Olsen, Jonathan B., Wan, Cuihong, Loppnau, Peter, El Bakkouri, Majida, Senisterra, Guillermo A., He, Hao, Huang, Haiming, Sidhu, Sachdev S., Emili, Andrew, Murphy, Shona, Mosley, Amber L., Arrowsmith, Cheryl H., Min, Jinrong, Greenblatt, Jack F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124035/
https://www.ncbi.nlm.nih.gov/pubmed/24997600
http://dx.doi.org/10.1038/nsmb.2853

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