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Apoptosis and the FLIP and NF-kappa B proteins as pharmacodynamic criteria for biosimilar TNF-alpha antagonists

Various criteria are necessary to assess the efficacy and safety of biological medications in order to grant companies the right to register these medications with the appropriate bodies that regulate their sale. The imminent expiration of the patents on reference biological products which block the...

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Detalles Bibliográficos
Autores principales: Urbano, Paulo César Martins, Soccol, Vanete Thomaz, Azevedo, Valderilio Feijó
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124053/
https://www.ncbi.nlm.nih.gov/pubmed/25114503
http://dx.doi.org/10.2147/BTT.S57253