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Propofol mediates signal transducer and activator of transcription 3 activation and crosstalk with phosphoinositide 3-kinase/AKT

We previously demonstrated that propofol, an intravenous anesthetic with anti-oxidative properties, activated the phosphoinositide 3-kinase (PI3K)/AKT pathway to increase the expression of B cell lymphoma (Bcl)-2 and, therefore the anti-apoptotic potential on cardiomyocytes. Here, we wanted to deter...

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Detalles Bibliográficos
Autores principales: Shravah, Jayant, Wang, Baohua, Pavlovic, Marijana, Kumar, Ujendra, Chen, David DY, Luo, Honglin, Ansley, David M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124059/
https://www.ncbi.nlm.nih.gov/pubmed/25105067
http://dx.doi.org/10.4161/jkst.29554

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