Cargando…

Propofol mediates signal transducer and activator of transcription 3 activation and crosstalk with phosphoinositide 3-kinase/AKT

We previously demonstrated that propofol, an intravenous anesthetic with anti-oxidative properties, activated the phosphoinositide 3-kinase (PI3K)/AKT pathway to increase the expression of B cell lymphoma (Bcl)-2 and, therefore the anti-apoptotic potential on cardiomyocytes. Here, we wanted to deter...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shravah, Jayant, Wang, Baohua, Pavlovic, Marijana, Kumar, Ujendra, Chen, David DY, Luo, Honglin, Ansley, David M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124059/ https://www.ncbi.nlm.nih.gov/pubmed/25105067 http://dx.doi.org/10.4161/jkst.29554

Ejemplares similares

Propofol pretreatment attenuates lipopolysaccharide-induced acute lung injury in rats by activating the phosphoinositide-3-kinase/Akt pathway
por: Zhao, L.L., et al.
Publicado: (2014)

A specific role for phosphoinositide 3-kinase and AKT in osteoblasts?
por: McGonnell, Imelda M., et al.
Publicado: (2012)

Phosphoinositide 3-Kinase/Akt Signaling and Redox Metabolism in Cancer
por: Koundouros, Nikos, et al.
Publicado: (2018)

The Role of Phosphoinositide 3-Kinase-Akt Signaling in Virus Infection
por: Cooray, Samantha
Publicado: (2007)

The Basal Transcription Complex Component TAF3 Transduces Changes in Nuclear Phosphoinositides into Transcriptional Output
por: Stijf-Bultsma, Yvette, et al.
Publicado: (2015)

Vav1 Transduces T Cell Receptor Signals to the Activation of Phospholipase C-γ1 via Phosphoinositide 3-Kinase-dependent and -independent Pathways
por: Reynolds, Lucinda F., et al.
Publicado: (2002)

Inhibitors of phosphoinositide 3-kinase (PI3K) and phosphoinositide 3-kinase-related protein kinase family (PIKK)
por: Huang, Xueqin, et al.
Publicado: (2023)

Disease Evolution and Response to Rapamycin in Activated Phosphoinositide 3-Kinase δ Syndrome: The European Society for Immunodeficiencies-Activated Phosphoinositide 3-Kinase δ Syndrome Registry
por: Maccari, Maria Elena, et al.
Publicado: (2018)

Phosphoinositide-3 Kinase-Akt Pathway Controls Cellular Entry of Ebola Virus
por: Saeed, Mohammad F., et al.
Publicado: (2008)

Respiratory Manifestations of the Activated Phosphoinositide 3-Kinase Delta Syndrome
por: Condliffe, Alison M., et al.
Publicado: (2018)

Bauerane Induces S-Phase Cell Cycle Arrest, Apoptosis, and Inhibition of Proliferation of A549 Human Lung Cancer Cells Through the Phosphoinositide 3-Kinase (PI3K)/AKT and Signal Transducer and Activator of Transcription 3 (STAT3) Signaling Pathway
por: Chen, Qin, et al.
Publicado: (2020)

Antitumor effect of resveratrol on chondrosarcoma cells via phosphoinositide 3-kinase/AKT and p38 mitogen-activated protein kinase pathways
por: Dai, Zixun, et al.
Publicado: (2021)

MicroRNA-214 suppresses propofol-induced neuroapoptosis through activation of phosphoinositide 3-kinase/protein kinase B signaling by targeting phosphatase and tensin homolog expression
por: Guo, Xukeng, et al.
Publicado: (2018)

Berberine Induced Apoptosis of Human Osteosarcoma Cells by Inhibiting Phosphoinositide 3 Kinase/Protein Kinase B (PI3K/Akt) Signal Pathway Activation
por: CHEN, Zhi-Ze
Publicado: (2016)

Occurrence of B-cell lymphomas in patients with Activated Phosphoinositide 3-Kinase δ syndrome
por: Kracker, Sven, et al.
Publicado: (2014)

Class (I) Phosphoinositide 3-Kinases in the Tumor Microenvironment
por: Gyori, David, et al.
Publicado: (2017)

Phosphoinositide 3–kinase γ participates in T cell receptor–induced T cell activation
por: Alcázar, Isabela, et al.
Publicado: (2007)

Noncanonical regulation of insulin-mediated ERK activation by phosphoinositide 3-kinase γ
por: Mohan, Maradumane L., et al.
Publicado: (2017)

Natural Course of Activated Phosphoinositide 3-Kinase Delta Syndrome in Childhood and Adolescence
por: Bloomfield, Marketa, et al.
Publicado: (2021)

Unveiling molecular insights into the mechanism of activation of oncogenic phosphoinositide 3-kinase mutants
por: Krimmer, Stefan G., et al.
Publicado: (2022)

Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ
por: Chen, Chun-Liang, et al.
Publicado: (2023)

Deconvolution of bulk RNA sequencing in activated phosphoinositide 3‐kinase δ syndrome
por: Huang, Xia, et al.
Publicado: (2023)

Intranuclear Crosstalk between Extracellular Regulated Kinase1/2 and Signal Transducer and Activator of Transcription 3 Regulates JEG-3 Choriocarcinoma Cell Invasion and Proliferation
por: Morales-Prieto, Diana M., et al.
Publicado: (2013)

Protein Kinase Activity of Phosphoinositide 3-Kinase Regulates Cytokine-Dependent Cell Survival
por: Thomas, Daniel, et al.
Publicado: (2013)

Vav3 Modulates B Cell Receptor Responses by Regulating Phosphoinositide 3-Kinase Activation
por: Inabe, Kazunori, et al.
Publicado: (2002)

Class 3 phosphoinositide 3‐kinase promotes hepatic glucocorticoid receptor stability and transcriptional activity
por: Shibayama, Yui, et al.
Publicado: (2022)

Activated phosphoinositide 3‐dinase delta syndrome (APDS): An update
por: Lougaris, Vassilios, et al.
Publicado: (2022)

Arsenite-induced stress signaling: Modulation of the phosphoinositide 3′-kinase/Akt/FoxO signaling cascade()
por: Hamann, Ingrit, et al.
Publicado: (2013)

Lysophosphatidic Acid Signalling Regulates Human Sperm Viability via the Phosphoinositide 3-Kinase/AKT Pathway
por: Liao, Hao-Yu, et al.
Publicado: (2023)

Insulin and Insulin-like growth factor-1 can activate the phosphoinositide-3-kinase /Akt/FoxO1 pathway in T cells in vitro
por: Mirdamadi, Yasaman, et al.
Publicado: (2017)

Phosphoinositide 3-Kinase Inhibitor-Induced Hyperglycemia
por: Shey, Susan, et al.
Publicado: (2021)

p85β increases phosphoinositide 3-kinase activity and accelerates tumor progression
por: González-García, Ana, et al.
Publicado: (2012)

Tyrosol Suppresses Allergic Inflammation by Inhibiting the Activation of Phosphoinositide 3-Kinase in Mast Cells
por: Je, In-Gyu, et al.
Publicado: (2015)

Phosphoinositide-3 kinase gamma kinase activity significantly contributes to the pathophysiology of sepsis and multiorgan failure
por: Martin, Erica, et al.
Publicado: (2008)

Caspase-activated phosphoinositide binding by CNT-1 promotes apoptosis by inhibiting the AKT pathway
por: Nakagawa, Akihisa, et al.
Publicado: (2014)

Phosphoinositide-3-Kinase Is the Primary Mediator of Phosphoinositide-Dependent Inhibition in Mammalian Olfactory Receptor Neurons
por: Ukhanov, Kirill, et al.
Publicado: (2016)

The cardioprotection induced by lipopolysaccharide involves phosphoinositide 3-kinase/Akt and high mobility group box 1 pathways
por: Liu, Xiang, et al.
Publicado: (2010)

A novel tumor suppressor protein encoded by circular AKT3 RNA inhibits glioblastoma tumorigenicity by competing with active phosphoinositide-dependent Kinase-1
por: Xia, Xin, et al.
Publicado: (2019)

Phosphoinositides regulate the TCR/CD3 complex membrane dynamics and activation
por: Chouaki Benmansour, Nassima, et al.
Publicado: (2018)

Loss of phosphoinositide 3-kinase γ decreases migration and activation of phagocytes but not T cell activation in antigen-induced arthritis
por: Gruen, Michael, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_luqj6uiuv1kgt2dkvsd1s71rld