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Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells
An analysis of the model underpinning the description of the spread of HIV infection of CD4(+)T cells is examined in detail in this work. Investigations of the disease free and endemic equilibrium are done using the method of Jacobian matrix. An iteration technique, namely, the homotopy decompositio...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124211/ https://www.ncbi.nlm.nih.gov/pubmed/25136605 http://dx.doi.org/10.1155/2014/618404 |
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author | Atangana, Abdon Doungmo Goufo, Emile Franc |
author_facet | Atangana, Abdon Doungmo Goufo, Emile Franc |
author_sort | Atangana, Abdon |
collection | PubMed |
description | An analysis of the model underpinning the description of the spread of HIV infection of CD4(+)T cells is examined in detail in this work. Investigations of the disease free and endemic equilibrium are done using the method of Jacobian matrix. An iteration technique, namely, the homotopy decomposition method (HDM), is implemented to give an approximate solution of nonlinear ordinary differential equation systems. The technique is described and illustrated with numerical examples. The approximated solution obtained via HDM is compared with those obtained via other methods to prove the trustworthiness of HDM. Moreover, the lessening and simplicity in calculations furnish HDM with a broader applicability. |
format | Online Article Text |
id | pubmed-4124211 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-41242112014-08-18 Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells Atangana, Abdon Doungmo Goufo, Emile Franc Biomed Res Int Research Article An analysis of the model underpinning the description of the spread of HIV infection of CD4(+)T cells is examined in detail in this work. Investigations of the disease free and endemic equilibrium are done using the method of Jacobian matrix. An iteration technique, namely, the homotopy decomposition method (HDM), is implemented to give an approximate solution of nonlinear ordinary differential equation systems. The technique is described and illustrated with numerical examples. The approximated solution obtained via HDM is compared with those obtained via other methods to prove the trustworthiness of HDM. Moreover, the lessening and simplicity in calculations furnish HDM with a broader applicability. Hindawi Publishing Corporation 2014 2014-07-17 /pmc/articles/PMC4124211/ /pubmed/25136605 http://dx.doi.org/10.1155/2014/618404 Text en Copyright © 2014 A. Atangana and E. F. Doungmo Goufo. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Atangana, Abdon Doungmo Goufo, Emile Franc Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells |
title | Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells |
title_full | Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells |
title_fullStr | Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells |
title_full_unstemmed | Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells |
title_short | Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells |
title_sort | computational analysis of the model describing hiv infection of cd4(+)t cells |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124211/ https://www.ncbi.nlm.nih.gov/pubmed/25136605 http://dx.doi.org/10.1155/2014/618404 |
work_keys_str_mv | AT atanganaabdon computationalanalysisofthemodeldescribinghivinfectionofcd4tcells AT doungmogoufoemilefranc computationalanalysisofthemodeldescribinghivinfectionofcd4tcells |