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Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells

An analysis of the model underpinning the description of the spread of HIV infection of CD4(+)T cells is examined in detail in this work. Investigations of the disease free and endemic equilibrium are done using the method of Jacobian matrix. An iteration technique, namely, the homotopy decompositio...

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Detalles Bibliográficos
Autores principales: Atangana, Abdon, Doungmo Goufo, Emile Franc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124211/
https://www.ncbi.nlm.nih.gov/pubmed/25136605
http://dx.doi.org/10.1155/2014/618404
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author Atangana, Abdon
Doungmo Goufo, Emile Franc
author_facet Atangana, Abdon
Doungmo Goufo, Emile Franc
author_sort Atangana, Abdon
collection PubMed
description An analysis of the model underpinning the description of the spread of HIV infection of CD4(+)T cells is examined in detail in this work. Investigations of the disease free and endemic equilibrium are done using the method of Jacobian matrix. An iteration technique, namely, the homotopy decomposition method (HDM), is implemented to give an approximate solution of nonlinear ordinary differential equation systems. The technique is described and illustrated with numerical examples. The approximated solution obtained via HDM is compared with those obtained via other methods to prove the trustworthiness of HDM. Moreover, the lessening and simplicity in calculations furnish HDM with a broader applicability.
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spelling pubmed-41242112014-08-18 Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells Atangana, Abdon Doungmo Goufo, Emile Franc Biomed Res Int Research Article An analysis of the model underpinning the description of the spread of HIV infection of CD4(+)T cells is examined in detail in this work. Investigations of the disease free and endemic equilibrium are done using the method of Jacobian matrix. An iteration technique, namely, the homotopy decomposition method (HDM), is implemented to give an approximate solution of nonlinear ordinary differential equation systems. The technique is described and illustrated with numerical examples. The approximated solution obtained via HDM is compared with those obtained via other methods to prove the trustworthiness of HDM. Moreover, the lessening and simplicity in calculations furnish HDM with a broader applicability. Hindawi Publishing Corporation 2014 2014-07-17 /pmc/articles/PMC4124211/ /pubmed/25136605 http://dx.doi.org/10.1155/2014/618404 Text en Copyright © 2014 A. Atangana and E. F. Doungmo Goufo. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Atangana, Abdon
Doungmo Goufo, Emile Franc
Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells
title Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells
title_full Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells
title_fullStr Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells
title_full_unstemmed Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells
title_short Computational Analysis of the Model Describing HIV Infection of CD4(+)T Cells
title_sort computational analysis of the model describing hiv infection of cd4(+)t cells
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124211/
https://www.ncbi.nlm.nih.gov/pubmed/25136605
http://dx.doi.org/10.1155/2014/618404
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